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PUBLICATIONS:

PUBLICATIONS :

2024

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43. Shijie Yang†, Fengqing Hu†, Tianjing Xu, Fanjie Lin, Jinsong Han*, Fei Li* :                                      

Stacking Transformation-Triggered Circularly Polarized Luminescence Reversion in γ-Cyclodextrins-Pyrene Co-assembly:

Chemistry – A European Journal, 2024,Accepted

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41. Yang Yu†, Weiwei Ni†, Qin Hu†, Huihai Li, Yi Zhang, Xu Gao, Lingjia Zhou, Shuming Zhang, Shuoyang Ma, Yanliang Zhang, Hui Huang*,

Fei Li,* Jinsong Han* :                                               

A Dual Fluorescence Turn-On Sensor Array Formed by Poly(para-aryleneethynylene) and Aggregation-Induced Emission Fluorophores for Sensitive Multiplexed Bacterial Recognition​:

Angewandte Chemie International Edition. 2024, 63,16,e202318483

Angewandte Chemie. 2024, 136,e202318483

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38. Shijie Yang, Fei Li*, Qihuan Li, Jinsong Han* and Yixiang Cheng*:
Chiral Coassembly-Activated CPL Ampification Promoted from Electrostatic and Arene-Perfluoroarene Interactions:

ACS Applied Optical Materials, 2023, 1, 8, 1492–1500

 

 

 

 

 

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40. Weiwei Ni, Yang Yu, Xu Gao, Yang Han, Wenhui Zhang, Zerui Zhang, Wenqi Xiao, Qin Hu, Yanliang Zhang, Hui Huang, Fei Li*,

Mingqi Chen*, Jinsong Han* :                                                   

Multilocus Distance-regulated Sensor Array for Recognition of Polyphenols via Machine Learning and Indicator Displacement Assay:

Analytical Chemistry, 2024, 96, 1, 301–308​​​​                              ------洋,韩仰,张泽瑞为本科生(国家级大学生创新创业训练计划)

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37. Yike Yang, Yumei Ji, Xu Han, Yunxin Long, Callum Stewart, Yiqiang Wen, Hok Yeung Lee,

Tian Cao, Jinsong Han, Sijie Chen, Linxian Li:
Implement the Materials Genome Initiativ
e: Machine Learning Assisted Fluorescent Probe De-

sign for Cellular Substructure Staining:

Advanced Materials Technologies. 2023, 2300427.

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36. Shijie Yang, Shuming Zhang, Fengqing Hu, Jinsong Han*, and Fei Li*:
Circularly Polarized Luminescence Polym
ers: From Design to Applications
Coordination Chemistry Reviews, 2023, 485, 215116.

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35. Jiaojiao Qin†, Hao Wang†, Yu Xu†, Fangfang Shi, Shijie Yang, Hui Huang, Jun Liu, Callum Stewart, Linxian Li, Fei Li, Jinsong Han*,

Wenwen Wu*: A Simple Array Integrating Machine Learning for Identification of Flavonoids and Red Wines:

RSC Advances,  2023, 13, 8882 - 8889.

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39. Yang Yu†, Fangfang Shi†, Yi Zhang, Fei Li* and Jinsong Han*:

Optical Sensor Array for the Discrimination of Liquors:

Journal of Future Foods, 2024, 4, 1, 48-60 (Invited Review特约)

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42. Yang Yu†, Weiwei Ni†, Xiao Shi, Ying Bia, Huihai Li, Mai Liu, Weijia Chen, Meng Zhang, Shujun Jiang, Mingqi Cheng, Fei Li, Yanliang Zhang, Zhijun Zhang, Hui Huang, Jinsong Han*:                                               

A Supramolecular Fluorescent Sensor Array Composed of Conjugated fluorophores and Cucurbit[7]uril for Bacterial Recognition​:

Analytical Chemistry, 2024, Accepted. (DOI: 10.1021/acs.analchem.4c02625)

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34. Lian Xu†, Hao Wang, Wenqi Xiao, Wenhui Zhang, Callum Stewart, Hui Huang*, Fei Li*, and Jinsong Han*
PAMAM Dendrime
r-based Tongue Rapidly Identifies Multiple Antibiotics in Milk:

Sensors and Actuators: B. Chemical,  2023, 382, 133519.

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33. Yu Xu, Cheng Qian, Yang Yu, Shijie Yang, Fangfang Shi, Lian Xu, Xu Gao, Yuhang Liu, Hui Huang, Callum Stewart, Fei Li,* and Jinsong Han*:
Machine Learning-Assisted Nanoenzyme/Bioenzyme Dual-Coupled Array for Rapid Detection of Amyloids:
Analytical Chemistry, 2023, 95, 10, 4605–4611. 

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32. Weiwei Ni†, Lingjia Zhou†, Hao Wang, Fei Li* and Jinsong Han*:

Research progress based on the construction and application of nucleic acid and protein biomolecular sensor arrays and the application of rapid detection:

Synthetic Biology Journal, 2023, 4, 1, 185-203.  (Invited Review特约

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31. Wenyu Cui†, Ruoxi Zhao†, Lulu Han, Weiwei Ni,Fei Li* and Jinsong Han*:

Advances in the Study of New BCR-ABL Kinase Inhibitors:

Acta Pharmaceutica Sinica, 2023, 58, 2, 258-273.

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30. Fei Li†, Lingjia Zhou†, Xu Gao, Weiwei Ni, Jiabao Hu, Meicen Wu, Shouwang Chen, Jinsong Han* and Jin Wu*:

A Multichannel Fluorescent Tongue for Amyloid-β Aggregates Detection:

International Journal of Molecular Sciences, 2022, 23,23, 14562.  (Invited Article特邀)

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29. Hao Wang†, Lingjia Zhou†, Jiaojiao Qin, Jiahao Chen, Callum Stewart, Yimin Sun(本科生/国家大创), Hui Huang, Lian Xu, Linxian Li, Jinsong Han* and Fei Li*:
One-Component Multichannel Sensor Array for Rapid Identification of Bacteria:

Analytical Chemistry, 2022, 94, 28, 10291–10298.

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27. Fei Li†, Callum Stewart†, Shijie Yang, Fangfang Shi, Wenyu Cui, Shuming Zhang, Hao Wang, Hui Huang*, Mingqi Chen*, Jinsong Han*
Optical Sensor Array for the Early Diagnosis of Alzheimer's Disease:

Frontiers in Chemistry, 2022, 10, 874864.  (Invited Mini Review特邀)

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28. Lian Xu†, Hao Wang†, Yu Xu, Wenyu Cui, Weiwei Ni, Mingqi Chen, Hui Huang, Callum Stewart, Linxian Li, Fei Li* and Jinsong Han*:

Machine Learning-Assisted Sensor Array Based on PAMAM dendrimers for Diagnosing Alzheimer's Disease:

ACS Sensors, 2022, 7, 5, 1315–1322.

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26. Hao Wang†, Mingqi Chen†, Yimin Sun, Lian Xu, Fei Li* and Jinsong Han*:

Machine Learning-Assisted Pattern Recognition of Amyloid Beta Aggregates with Fluorescent Conjugated Polymers and Graphite Oxide Electrostatic Complexes:   

Analytical Chemistry, 2022, 94, 6, 2757–2763.  

Selected as “Cover” by the editors

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25. Bai Xixi, Han Chenggang, Xu Ying, Jinsong Han, Chongjiang Cao, Shujie Cheng*:

Research Progress of Dietary Intervention Strategies for Irritable Bowel Syndrome:

Science and Technology of Food Industry. 2022, 43, 16, 421-431.

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24. Bin Zheng, Xianhuang Li, Sheng Xie, Shuodong Wang, Weiming Lai, Zhibiao Zhou, Qing Liu, Yujiao Yang, Bei Hou, Weiwei Ni, Jinsong Han, Yong Liu, Zebing Zeng, Tao Wang, Ben Zhong Tang*:

A Fluorogenic Labeling of Live Viruses.

ChemRxiv  PubDate : 2021-06-22 , DOI: 10.33774/chemrxiv-2021-bqkwt

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23. Zheng Li*, Qingshan Wei, Jinsong Han:

Array-Based Sensing Techniques for Clinical, Agricultural Biotechnology, and Environmental Analysis:

Frontiers in Chemistry. 2021, 3, 9, 654707.  (Invited特邀)

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22. Lei Miao, Linxian Li, Yuxuan Huang, Derfogail Delcassian, Jasdave Chahal, Jinsong Han, Yunhua Shi, Kaitlyn Sadtler, Wenting Gao, Jiaqi Lin, Joshua C. Doloff, Robert Langer, and Daniel G. Anderson*:

Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation.

Nature Biotechnology. 2019, 37, 10, 1174-1185. 

--2021
--2020
--2019
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21. Ngoc D.B. Le, Arvind K. Singla, Yingying Geng, Jinsong Han, Kai Seehafer, Gyan Prakash, Daniel F. Moyano, Charlene M. Downey, Michael J. Monument, Doha Itani, Uwe H. F. Bunz, Frank R Jirik and Vincent Rotello*:

Simple and Robust Polymer-based Sensor for Rapid Cancer Detection using Serum.

Chemical Communications, 2019, 55, 76, 11458-11461. 

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_____________________________________________________________________________________________________________________________20. Hao Liu, Balakrishna Moku, Fei Li, Jiabing Ran, Jinsong Han, Sihui Long*, Gao-Feng Zha* and Hua-Li Qin:

Stereoselective Construction of Nitrile-Substituted Cyclopropanes from 2-Substituted Ethenesulfonyl Fluorides via carbon-Sulfur Bond Cleavage.

Advanced Synthesis & Catalysis. 2019, 361, 19, 4596-4601.

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19. F. Li#, Jinsong Han#, T. Cao, W. Lam, B. Fan, W. Tang, S. Chen, K. L. Fok* and L. Li*:
Design of self-assembly dipeptide hydrogels and machine learning via their chemical features:
Proceedings of the National Academy of Sciences, PNAS. 2019, 116, 11259-11264. 

Highlighted in “MIT Technology Review”. 

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18. X. Fan, W. Xu, Jinsong Han, M. Ren, Y. Zhang, M. Wink, G. Wu*:

Antimicrobial peptide hybrid fluorescent proteins discriminate ten most frequent clinic isolates:

Biochimica et Biophysica Acta (BBA) - General Subjects. 2019, 6, 118-1166.

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17. B. Wang, Jinsong Han, H. Zhang, A. Biella, M. Bender, K. Seehafer, U. H. F. Bunz*:

Detecting Counterfeit Brandies.

Chemistry – A European Journal. 2018, 24, 17361-17366.

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16. B. Wang, Jinsong Han, N. M. Bojanowski, M. Bender, C. Ma, K. Seehafer, A. Herrmann, U. H. F. Bunz*:
An Optimized Sensor Array Identifies All Natural Amino Acids.
ACS Sensors. 2018, 3, 1562-1568.

Selected as Cover” by the editors

--2018

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15. B. Wang#, Jinsong Han#, M. Bender, S. Hahn, K. Seehafer, U. H. F. Bunz*:

Poly(para-phenyleneethynylene)-Sensor Arrays Discriminate 22 Different Teas.

ACS Sensors. 2018, 3, 504–511.

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14. Jinsong Han#, H. Cheng#, B. Wang#, M. S. Braun, X. Fan, M. Bender, W. Huang, C. Domhan, W. Mier, T. Lindner, Kai Seehafer, M. Wink, Uwe. H. F. Bunz*:
Polymer/Peptide Complex-Based Sensor Array Discriminates Bacteria in Urine.
Angewandte Chemie International Edition. 2017, 56, 15246-15251.

Angewandte Chemie. 2017, 129, 15448-15453.

Highlighted as a Hot Paper” by the editors.

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13. B. Wang#, Jinsong Han#, C. Ma, M. Bender, K. Seehafer, A. Herrmann, U. H. F. Bunz*:
A Simple Optoelectronic Tongue Discriminates Amino Acids.
Chemistry – A European Journal. 201
7, 23, 12471-12474.

Highlighted as a “Hot Paper” by the editors.

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12. Jinsong Han, C. Ma, B. Wang, M. Bender, M. Bojanowski, M. Hergert, K. Seehafer, A. Herrmann, U. H.F. Bunz*:
A Hypothesis-Free Sensor Array Discriminates Whiskies for Brand, Age, and Taste.
Chem (CellPress), 2017, 2, 817-824.

Previewed Article by Prof. V. M. Rotello. Chem (Cell Press). 2017, 2, 755-756.

Highlighted in over 100 Newspapers, Journals, Radio and TV programs (Partially Selected):

Science News | AAAS, EurekAlert | AAAS, Chemical & Engineering News 2017,96(24) p9, New Scientist, BBC (Interview), Cell (Interview), Deutschlandfunk (Interview), CAMPUS TV (TV Interview), Heidelberg University Press Release, Phys.org, ScienceNewsline, Popular Science, The Verge, Trend Hunter, Inverse, GongSters, RawStory, D'MARGE, Daily Record, Digital Trends, The Register, Daily Mail Online, Woles.Net, LabManager, Quo.es, FakeNewsMatters.org, New Atlas, CGTN, CNET, YAHOO News, RocketNews, Mid-Day, Longroom.com, The Financial Express, News of the hour, Daily Messenger, Cetus News, The Asian Age, Asia Pacific Daily, Atlas Obscura, SOGO Tech News, Interesting Engineering, Rush Hour Daily News, China.org.cn, true-news.info, EOS Wetenschap, TrueViralNews, LaboratoryEquipment.com, GeekJournal.net, HealthMedicinet, Deccan Herald, SCMP, Technowize, Dotemirates, Pressreader, Mic.com. InsideHook, Orange by Handelsblatt, Deutschlandfunk, Engadget Deutschland, Rhein Neckar Zeitung, Spektrum.de, Zee News, naked-science.ru, BRIGHT.nl, N+1, Giornale di Scienza, Actualité Houssenia Writing, Gizmodo India, Deccan Chronicle, India TV, cnBeta, XINHUANET (新华网), CGTN (中国国际电视台), News.cn(新华社), Sciencenet(科学网新闻), X-MOL(新闻), THE PAPER(澎湃新闻), Sina(新浪新闻), Sohu(搜狐新闻), etc.

--2017
--2016

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11. B. Wang#, Jinsong Han#, M. Bender, K. Seehafer, U. H. F. Bunz*:

Array-Based Sensing of Explosives by Water-Soluble Poly(p-phenyleneethynylene)s".

Macromolecules, 2017, 50, 4126-4131.

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10.  Jinsong Han, B. Wang, M. Bender, J. Pfisterer, W. Huang, K. Seehafer, M. Yazdani, V. M. Rotello, C. M. Rotello, U. H. F. Bunz*:

Fingerprinting antibiotics with PAE-based fluorescent sensor arrays.

Polymer Chemistry, 2017, 8, 2723-2732.

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9. W. Huang, E. Smarsly, Jinsong Han, M. Bender, K. Seehafer, I. Wacker, R. Schroeder, U. H. F. Bunz*:

Truxene-Based Hyperbranched Conjugated Polymers: Fluorescent Micelles Detect Explosives in Water.

ACS Applied Materials & Interfaces. 2017, 9, 3068-3074.

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8. Jinsong Han, B. Wang, M. Bender, S. Kushida, K. Seehafer, U. H. F. Bunz*:

Poly(aryleneethynylene) Tongue Identifies Nonsteroidal Anti-inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs.

ACS Applied Materials & Interfaces. 2017, 9, 790–797.

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7.  Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz*:
"Poly(p-phenyleneethynylene)-based tongues discriminate fruit juices".
Analyst. 2017, 142, 537-543.

Highlighted in "ChemistryWorld" from RSC

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6.  Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz*:

Water-Soluble Poly(p-aryleneethynylene)s: A Sensor Array Discriminates Aromatic Carboxylic Acids.

ACS Applied Materials & Interfaces. 2016, 8, 20415–20421.

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5.  Jinsong Han, M. Bender, K. Seehafer, U. H. F. Bunz*:

"Identification of White Wines by using Two Oppositely Charged Poly(p-phenyleneethynylene)s Individually and in Complex".

Angewandte Chemie International Edition. 2016, 55, 7689-7692.
Angewandte Chemie
2016, 128, 7820–7823.

Highlighted in Angew. Chem. Int. Ed. Press Release, Chemical & Engineering News 2016, 94(26), 9, Analytik-News, ChemistryViews, Heidelberg University Press, X-MOL(新闻), PHYSORG news, chemie.de, Yumda, EATON, WijnWijs.eu, IDW, analytica-world.com, q-more.chemie.de, Spektrum.de, LABORWELT, Pro-Physik.de, innovations-report, etc.

 

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4.  Jinsong Han, M. Bender, S. Hahn, K. Seehafer, U. H. F. Bunz*:

Polyelectrolyte Complexes Formed from Conjugated Polymers: Array-Based Sensing of Organic Acids.

Chemistry – A European Journal. 2016, 22, 3230-3233.

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3. Y. Chen, L. Zhang, C. Yang, Jinsong Han, C. Wang, Y. Zhou, J. Lv, Y. Song* and J. Zhu*:

Discovery of Benzenesulfonamide Derivatives as Potent PI3K/mTOR Dual Inhibitors with In Vivo Efficacies against Hepatocellular Carcinoma.

Bioorganic & Medicinal Chemistry. 2016, 24, 957-966.

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2. Jinsong Han#, Y. Chen#, C. Yang, T. Liu, M. Wang, H. Xu, L. Zhang, C. Zheng, Y. Song*, J. Zhu*:

Structure-based Optimization Leads to the Discovery of NSC765844, A Highly Potent, Less Toxic and Orally Efficacious dual PI3K/mTOR Inhibitor.

European Journal of Medicinal Chemistry. 2016, 24, 957-966.

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1. Ying Chen, Jinsong Han, Chongqing Wang, Yunlong Song, Yonggang Zhou, Ju Zhu:*:

Review of research on dual PI3K-mTOR small molecular inhibitors:

Journal of Pharmaceutical Practice, 2014, 32, 5, 332-336.

PATENTS:

[1].   朱驹,黄晶晶,陈颖,韩进松,郑灿辉,周有骏,吕加国,王重庆,周浩,田巍,孙囡囡; 3,4-二氢异喹啉类抗肿瘤化合物及其制备方法与应用。CN103396361B(2013)

[2].   朱驹,宋云龙,韩进松,陈颖,吕加国,周有骏;N-(5-(喹啉-6-基)吡啶-3-基)苯磺酰胺衍生物、制备方法及治疗用途。    CN104918933A; WO2014067473A(2013)(转让上海医药集团股份有限公司)

[3].   Uwe.H.F. Bunz, Kai Seehafer, Jinsong Han, Markus Bender. Method for identifying a complex analyte. US20200025683A1; WO2018055056 A1 (2020)

[4].   李林鲜,查高峰,韩进松; 氨基脂质化合物、其制备方法和应用。CN113968968B(申请:2020.04.15);ZL2020102939429(授权:2024.01.26)(转让深圳深信生物科技有限公司)

[5].   韩进松,王浩,李飞,马宗辉,黄慧; 静电复合物荧光阵列传感器及用途。CN112143178B(申请:2020.09.24);ZL2020110197007(授权:2022.06.28)

[6].   韩进松,李飞,秦娇娇,黄慧,王浩; 基于苝二酰亚胺类衍生物的荧光阵列传感器及其构建方法与应用。CN112924426B (申请:2021.01.28);ZL202110117917X(授权:2022.11.08)

[7].   韩进松,李飞,许莲,王浩,黄慧;基于芘取代化合物的荧光阵列传感器及其构建方法与应用。CN112945917B (申请:2021.01.28);ZL2021101173991(授权:2023.05.23)
[8].   韩进松,崔文禹,黄慧,刘宇航,缪顺童,李飞; 一种具有蛋白激酶抑制活性的(杂)芳基酰胺类化合物。CN114149409B (申请:2021.11.22);ZL2021114005941(授权:2024.03.22)

[9].   韩进松,施芳芳,黄慧,刘宇航,缪顺童,倪伟伟; 一种非共价BTK激酶抑制剂及其生物用途。CN114920744B (申请:2021.11.22);ZL2021113918882(授权:2024.05.07)

[10].  韩进松,崔文禹,赵若熙,韩路路,刘宇航,张文慧,缪顺童; 一种(杂)芳基酰胺类化合物。CN115109048B (申请:2022.08.10);ZL2022109536983(授权:2023.12.08)

[11].   韩进松,张怡,施芳芳,张文慧;一种作为BTK激酶抑制剂的化合物及其制备方法与用途 。CN115894500A (申请:2022.11.02)

[12].   韩进松,周玲佳,李飞,王浩;多通道荧光阵列传感器及其构建和使用方法。CN116203006A(申请:2023.03.15)

[13].   韩进松,施芳芳,张怡,刘宇航,张文慧,黄慧;一种作为非共价BTK激酶抑制剂的化合物及其生物用途。CN116375715A(申请:2023.04.06)

[14].   韩进松,余洋,李飞,李汇海;静电复合物多通道荧光阵列传感器、其制备方法及用途。CN116593437A(申请:2023.05.18)

[15].   陈明琪,余洋,倪伟伟,韩仰,张泽锐,周玲佳,余洁,张馨月,农碧聪,李飞,韩进松;复合物荧光阵列传感器及其构建方法和应用。CN116735555A (申请:2023.06.08)大学生创新性项目

[16].   韩进松,倪伟伟,张书铭,肖文琪;多通道荧光阵列传感器及其构建方法和使用方法。CN116952911A(申请:2023.06.08)

[17].   韩进松,施芳芳,刘宇航,张怡,黄慧,张文慧,一种(4-苯氧基苯基)(吡咯并嘧啶-5-基)甲酮类化合物及其制备方法和应用。CN116947863A (申请:2023.06.13)

[18].   李飞,张馨月,余洁,张书铭,韩进松,农碧聪,余洋,一种基于比色阵列传感器的多羟基化合物的检测方法,申请号:2023107323652 (申请:2023.07)大学生创新性项目

[19].   韩进松,张文慧,吴斐华,黄慧,车赛,林范洁,周玲佳,肖文琪,高旭,苯胺基嘧啶并杂环类化合物及其制备方法、药物组合物和应用。CN117327077A (申请:2023.10.07)​

[20].   韩进松,李飞,张书铭,胡锋清,倪伟伟,高旭,一种静电复合荧光阵列传感器元件库及其构建方法和应用。CN117347622A(申请:2023.10.07)​

[21].   韩进松,缪顺童,张文慧,王路,黄慧,一种逆转低分子肝素抗凝活性的三嗪化合物及其制备方法和应用。CN117417328A(申请:2023.10.19)

[22].  韩进松,王路,张文慧,缪顺童,黄慧,三嗪骨架小分子肝素逆转剂及其制备方法与用途。CN117624137A(申请:2023.12.04)

[23].  韩进松,倪伟伟,匡勇斌,车赛,刘迈,赵小演,张书铭,肖文琪,一种多通道荧光阵列传感器及其制备方法和其使用方法,申请号:2024100255818(申请:2024.01)

Patents (专利):
2024
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